000 01464nam a2200241 4500
001 391203
090 _a391203
100 _a20121012d2012 y0pory50 ba
101 _aeng
200 _aTaq mutants engineered for forensics
_bRecurso eletrónico
_fMilko Kermekchiev
210 _aSaint Louis, MO
_ced. do a.
_d2012
215 _a1 CD-ROM
_d12 cm
300 _aResearch report submitted to the U.S. Department of Justice, NIJ Award No. 2008-DN-BX-K299. Resumo inserto na publicação. Ficheiro de 1,58 MB em formato PDF (43 p.). Disponível também em: https://www.ncjrs.gov/pdffiles1/nij/grants/239074.pdf. Acedido a 12 de outubro de 2012.
330 _aMajor problems with PCR-based forensic tests are false negative results and low sensitivity caused by residual blood, soil or other PCR inhibitors present in the sample. We proposed to apply our novel genetically-engineered mutants of Taq DNA polymerase, highly resistant to PCR inhibitors, to direct DNA analysis of forensic samples. In many cases, this approach can eliminate the need to purify DNA prior to PCR and decrease the time, lower the cost, and increase the efficiency of forensic DNA testing.
606 _aANÁLISE LABORATORIAL
_9326721
606 _aADN
_9243660
606 _aCIÊNCIA FORENSE
_9321508
700 _aKERMEKCHIEV
_bMilko
_9356892
955 _xOferta