000			02202nam a2200253 4500
001			390983
090			_a390983
100			_a20120601d2012 y0pory50 ba
101			_aeng
200			_aInvestigations on the use of Samplematrix to stabilize crime scene biological samples for optimized analysis and room temperature storage _bRecurso eletrónico _fKatherine A. Roberts, Donald J. Johnson
210			_a[S.l.] _ced. do a. _d2012
215			_a1 CD-ROM _d12 cm
300			_aResearch report submitted to the U.S. Department of Justice Award no. 2007-DN-BX-K172. Ficheiro de 7,86 MB em formato PDF (296 p.). Disponível também em: https://www.ncjrs.gov/pdffiles1/nij/grants/237838.pdf. Acedido a 01 de junho de 2012.
330			_aStorage and preservation of biological evidence are key forensic issues that are currentlyunder investigation in anticipation of more cost saving and effective stabilization methods. Onceevidence has been identified and collected at a crime scene, it is typically stored for analysislater. Storing biological evidence at subzero temperatures is one of the current methodsemployed to prevent DNA degradation until time of analysis; however, previous studies haveshown that freezing biological evidence does not completely cease the degradation process. Inaddition, it has been shown that repeated freezing and thawing of biological evidence may add tothe degradation effects. The research presented here evaluates a proprietary platform technologyfor the dry storage of biological materials at ambient temperature. The technology behind thisroom temperature stability is primarily adopted from natural principles and is based on the DNAstabilizing properties of small molecules such as trehalose. Three non-lysis formulations (SM1,SM2, and SM3) and one lysis formulation were evaluated with approximately 7,500 samples.
606			_aPRESERVAÇÃO DA PROVA _9302776
606			_aADN _9243660
606			_aANÁLISE DE VESTÍGIOS _9320649
606			_aBIOLOGIA FORENSE _91092
700			_aROBERTS _bKatherine A. _9356784
701			_aJOHNSON _bDonald J. _9356785
955			_xOferta