1.ª edição publicada em 1949 com o título: "Organic chemistry in pharmacy".

1. Introduction (Ole Gisvold, Charles O. Wilson); 2. Physicochemical properties in relation to biological action (T. C. Daniels, E. C. Jorgensen); 3. Metabolic changes of drugs and related organic compounds (T. C. Daniels, E. C. Jorgensen); 4. Anti-infective agents (Robert Doerge); 5. Phenols and their derivatives (Ole Gisvold); 6. Sulfonamides and sulfones with antibacterial action (Robert F. Doerge); 7. Surfactants and chelating agents (H. Wayne Schultz); 8. Antimalarials (Allen I. White); 9. Antibiotics (Arnold R. Martin); 10. Central nervous system depressants (T. C. Daniels, E. C. Jorgensen); 11. Central nervous system stimulants (T. C. Daniels, E. C. Jorgensen); 12. Adrenergic agents (Robert F. Doerge); 13. Cholinergic agents and related drugs (Ole Gisvold); 14. Autonomic blocking agents and related drugs (Taito O. Soine); 15. Diuretics (T. C. Daniels, E. C. Jorgensen); 16. Cardivascular agents (Robert F. Doerge); 17. Local anesthetic agents (Robert F. Doerge); 18. Histamine and antihistaminic agents (Robert F. Doerge); 19. Analgesic agents (Robert E. Willette); 20. Steroids and therapeutically related compounds (Dwight S. Fullerton); 21. Carbohydrates (Jaime N. Delgado); 22. Amino acids, proteins, enzymes and hormones with protein-like structure (Jaime N. Delgado); 23. Vitamins (Ole Gisvold); 24. Miscellaneous organic pharmaceuticals (Robert F. Doerge, Charles O. Wilson). Appendix A - Pharmaceutic aids. Appendix B - Amine salts. Appendix C - pKa's of drugs and reference compounds. Appendix D - Index names used by chemical abstracts service.