02202nam a2200253 4500 390983 390983 20120601d2012 y0pory50 ba eng Investigations on the use of Samplematrix to stabilize crime scene biological samples for optimized analysis and room temperature storage Recurso eletrónico Katherine A. Roberts, Donald J. Johnson [S.l.] ed. do a. 2012 1 CD-ROM 12 cm Research report submitted to the U.S. Department of Justice Award no. 2007-DN-BX-K172. Ficheiro de 7,86 MB em formato PDF (296 p.). Disponível também em: https://www.ncjrs.gov/pdffiles1/nij/grants/237838.pdf. Acedido a 01 de junho de 2012. Storage and preservation of biological evidence are key forensic issues that are currentlyunder investigation in anticipation of more cost saving and effective stabilization methods. Onceevidence has been identified and collected at a crime scene, it is typically stored for analysislater. Storing biological evidence at subzero temperatures is one of the current methodsemployed to prevent DNA degradation until time of analysis; however, previous studies haveshown that freezing biological evidence does not completely cease the degradation process. Inaddition, it has been shown that repeated freezing and thawing of biological evidence may add tothe degradation effects. The research presented here evaluates a proprietary platform technologyfor the dry storage of biological materials at ambient temperature. The technology behind thisroom temperature stability is primarily adopted from natural principles and is based on the DNAstabilizing properties of small molecules such as trehalose. Three non-lysis formulations (SM1,SM2, and SM3) and one lysis formulation were evaluated with approximately 7,500 samples. PRESERVAÇÃO DA PROVA 302776 ADN 243660 ANÁLISE DE VESTÍGIOS 320649 BIOLOGIA FORENSE 1092 ROBERTS Katherine A. 356784 JOHNSON Donald J. 356785 Oferta 0 PJCD_200_000000000000000 2022-06-06 PJCD200 422866 PJ PJ PJ1CD200_27 PJCD200 2022-06-06 0 MO Oferta