02627nam a2200181   4500001000700000100004100007101000800048200025800056210005000314215002000364300030700384330164200691606002702333606002402360606001402384700002702398701002002425390406  a20110720d2008       y0pory50      ba  aeng  aAnalysis of cocaine analytes in human hairbRecurso eletrónicoeevaluation of concentration ratios in different hair types, cocaine sources, drug-user populations, and surface-contaminated specimensefinal reportfJeri D. Ropero-Miller, Peter R. Stout  a[Research Triangle Park, NC]ced. do a.d2008  a1 CD-ROMd12 cm  a"Research report [prepared by] RTI International submitted to the U.S. Department of Justice. NIJ Award No. 2006-91774-NC-IJ". Ficheiro de 1,83 Mb em formato pdf (106 p.). Também disponível através de: https://www.ncjrs.gov/app/publications/abstract.aspx?ID=247513. Acedido a 20 de Julho de 2011.  aExecutive summary. Statement of the problem. Project purpose and goals. Research design and methods. Results. Stage I: Analysis of cocaine hydrochloride powders. Stage II: Analysis of hair from drug-user populations. Stage III: Contamination of hair with cocaine hydrochloride powders. Stage IV: Fortification of hair specimens with cocaine hydrochloride powders. Overall project summary. 1. Introduction. 1.1 Background. 1.2 Statement of the problem. 1.3 Review of the literature. 1.3.1 Use of hair drug testing. 1.3.2 Cocaine in hair. 1.3.3 Cocaine analyte concentration and ratio studies in drug-user populations. 1.3.4 Preliminary RTI sudies. 1.4 Rationale for the research (Statement of Hypothesis). 2. Research design and methods. 2.1 Stage I: Analysis of cocaine hydrochloride powders.  2.1.1 Experimental design. 2.1.2 Materials. 2.1.3 Methods. 2.1.4 Findings. 2.1.5 Conclusions. 2.2 Stage II: Analysis of hair from drug-user populations. 2.2.1 Experimental design. 2.2.2 Materials. 2.2.3 Methods. 2.2.4 Analytical procedures. 2.2.5 Modifications to the research design and rationale. 2.2.6 Findings. 2.2.7 Conclusions. 2.3 Stage III: Contamination of hair with refined illicit COC specimens. 2.3.1 Experimental design. 2.3.2 Conclusions. 2.4 Stage IV: Fortification of hair samples with cocaine hydrochloride in solution. 2.4.1 Experimental design. 2.4.2 Materials. 2.4.3 Methods. 2.4.4 Findings. 2.4.5 Conclusions. 3. Conclusions. 3.1. Discussion of findings. 3.1.1 Implications for policy and practice. 3.1.2 Implications for further research. 4. References. 5. Dissemination of research findings. Appendix A. List of figures.  aANÁLISE LABORATORIAL  aANÁLISE DE CABELO  aCOCAÍNA  aMILLERbJeri D. Ropero  aSTOUTbPeter R.