01979nam a2200181   4500001000700000090001100007100004100018101000800059200016900067311003900236330118300275461007501458606001601533606002701549606001901576710011301595995008901708378129  a378129  a20210621u           y0pory50      ba  aeng  aIdentification and determination of opioid peptides in biological material using the LC-QTOF-MS/MS techniquebRecurso eletrónicofMagdalena PoPławska ...[et al.]  aFicheiro de 520 KB em formato PDF.  a1. Introduction. 2. Case report. 3. Materials and methods. 3.1. Reagents and reference materials. 3.2. Analytical material. 3.3. Equipment and analytical parameters. 3.4. Qualitative analyses. 3.5. Quantitative analysis of deltorphin I and II in the secretion of Phyllomedusa bicolor. 3.6. Quantitative analysis of deltorphin I and II in blood. 3.7. Isolation of deltorphins from blood. 3.8. Preparation of samples for analysis. 3.9. Solutions for the validation of a method for the determination of deltorphin I and II. 3.10. Validation of the method for the determination of deltorphin I and II in “kambo”. 3.11. Validation of the method for determination of deltorphins in blood. 3.12. Estimating the degradation of deltorphins in blood. 4. results. 4.1. Identification of deltorphin I and II in the analysed sample of secretion from the frog Phyllomedusa bicolor. 4.2. Results obtained for evaluated validation parameters. 4.3. Determination of deltorphin I and deltorphin II concentrations in frog secretion. 4.4. Estimating the degradation of deltorphins in blood. 4.5. Determination of deltorphin I and deltorphin II concentration in the blood sample. 5. Conclusions.  d2018vVol. 116tProblems of Forensic Sciencesx1230-7483pp. 357–374  aTOXICOLOGIA  aANÁLISE LABORATORIAL  aESPECTROMETRIA  aIDENTIFICATION AND DETERMINATION OF OPIOID PEPTIDES IN BIOLOGICAL MATERIAL USING THE LC-QTOF-MS/MS TECHNIQUE  104PJCD_309_00000000000000052022-06-069405910aPJcPJkPJCD 309n2022-06-06o0rAP