01751nam a2200181 4500001000700000090001100007100004100018101000800059200006200067463019500129311019300324330086500517606002401382606002101406606002501427700002101452995009601473363047 a363047 a20170505u y0pory50 ba aeng aUse of reference materials in toxicologyfJennifer Button tIn: Forensic toxicology : drug use and misuse / ed. Susannah Davies, Atholl Johnston and David Holt. - Cambridge : The Royal Society of Chemistry, 2016. ISBN 978-1-78262-156-0. p. 370-399..  aIn: Forensic toxicology : drug use and misuse / ed. Susannah Davies, Atholl Johnston and David Holt. - Cambridge : The Royal Society of Chemistry, 2016. ISBN 978-1-78262-156-0. p. 370-399. aImportance of standardisation and harmonisation. The language of metrology. International System of Units. Metrological traceability. Measurement uncertainty. (Certified) reference materials. Quality control materials. Accreditation for reference material producers. Requirements for independent sources. Certificates of analysis. Structural confirmation. Purity. Guidance for selection and use of reference materials. Distinguishing between Chemicals and Reference Materials. Weighing environment. Neat versus Solutions. Free base versus Salts. Recovering reference materials from their container. Dealing with low quantity reference materials. Correct selection of solvent. Stability. Databases for certified reference materials. CCQM. Import and export of controlled drug reference materials. Import and export exemptions. Supplementary reading. References. aTOXICOLOGIA FORENSE aNORMALIZAÇÃO aOBRA DE REFERÊNCIA aBUTTONbJennifer 104PJ_24_000000000000000_B_15_3611052022-06-06aPJcPJkPJ24.B.15/36110n2022-06-06o0rAM