01620nam a2200157   4500001000700000100004100007101000800048200006200056463019500118311019300313330086500506606002401371606002101395606002501416700002101441363047  a20170505u           y0pory50      ba  aeng  aUse of reference materials in toxicologyfJennifer Button  tIn: Forensic toxicology : drug use and misuse / ed. Susannah Davies, Atholl Johnston and David Holt. - Cambridge : The Royal Society of Chemistry, 2016. ISBN 978-1-78262-156-0. p. 370-399..   aIn: Forensic toxicology : drug use and misuse / ed. Susannah Davies, Atholl Johnston and David Holt. - Cambridge : The Royal Society of Chemistry, 2016. ISBN 978-1-78262-156-0. p. 370-399.  aImportance of standardisation and harmonisation. The language of metrology. International System of Units. Metrological traceability. Measurement uncertainty. (Certified) reference materials. Quality control materials. Accreditation for reference material producers. Requirements for independent sources. Certificates of analysis. Structural confirmation. Purity. Guidance for selection and use of reference materials. Distinguishing between Chemicals and Reference Materials. Weighing environment. Neat versus Solutions. Free base versus Salts. Recovering reference materials from their container. Dealing with low quantity reference materials. Correct selection of solvent. Stability. Databases for certified reference materials. CCQM. Import and export of controlled drug reference materials. Import and export exemptions. Supplementary reading. References.  aTOXICOLOGIA FORENSE  aNORMALIZAÇÃO  aOBRA DE REFERÊNCIA  aBUTTONbJennifer